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A comparison of limited-angle CBCT photon-counting and flat-panel digital mammography in perceived detection and visualization of breast lesions

delete2026-03-01
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PRE
AI
S
Svahn, Tony Martin *
R
Radu Lesanu
A
Ander Biguri
A
Ast, Jennifer
DOI:10.1093/rpd/ncaf181delete
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Abstract

Abstract

En 中文
This investigation aimed to compare perceived lesion detectability and visibility between limited-angle cone-beam computed tomography (CBCT) photon-counting (PC) and flat-panel (FP) mammography at equivalent radiation-dose levels. Projection data were collected by rotating a lesion-containing, humanlike breast phantom and acquiring images at every other degree using both a PC and an FP system, resulting in 5-13 projections over an 8-24 degrees angular range. Feldkamp-Davis-Kress (FDK) and simultaneous iterative reconstruction technique (SIRT) algorithms were used to reconstruct three-dimensional (3D) volumes for each system. A reader study evaluated lesion detectability and visibility in the 3D data. PC-CBCT showed better detectability and visibility of masses compared to FP-CBCT, with 90% sensitivity versus 70% and an area under the visual grading curve (AUC(VGC)) of 0.66-0.71 (P < .05). FDK image volumes demonstrated improved calcification visibility (P < .05) with PC-CBCT over FP-CBCT; however, for SIRT, calcification visibility was lower (AUC(VGC) = 0.46). This study emphasizes the need to reassess photon-counting in 3D mammography to improve lesion detection and visibility.
Keywords:
DIAGNOSTIC-ACCURACY
TOMOSYNTHESIS
EFFICIENT
SOFTWARE
PERFORMANCE
QUALITY
VIEWDEX
UK

Journal

R
Radiation Protection Dosimetry
IF:
0.7
Papers:
139
Citations:
6.4K

Organization

U
university of cambridge
Scholars:
6.8K
Papers: 3.2K
Citations: 3
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