A cortical network for semantics: (de)constructing the N400

Ellen Lau

doi:10.1038/nrn2532

2008-12-01

1.4K

PRE

DOI：10.1038/nrn2532

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摘要

En 中文

Measuring event-related potentials (ERPs) has been fundamental to our understanding of how language is encoded in the brain. One particular ERP response, the N400 response, has been especially influential as an index of lexical and semantic processing. However, there remains a lack of consensus on the interpretation of this component. Resolving this issue has important consequences for neural models of language comprehension. Here we show that evidence bearing on where the N400 response is generated provides key insights into what it reflects. A neuroanatomical model of semantic processing is used as a guide to interpret the pattern of activated regions in functional MRI, magnetoencephalography and intracranial recordings that are associated with contextual semantic manipulations that lead to N400 effects.

Keyword:

EVENT-RELATED POTENTIALS

LEFT PREFRONTAL CORTEX

MEDIAL TEMPORAL-LOBE

DEPTH-RECORDED POTENTIALS

BRAIN POTENTIALS

TIME-COURSE

SENTENCE COMPREHENSION

LANGUAGE COMPREHENSION

WORD RECOGNITION

FUNCTIONAL MRI

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Nature Reviews Neuroscience

IF:

26.7

论文数:

4.0K

被引数:

4.8W

机构

University System of Maryland

学者数:

6.5W

论文数: 5.6W

被引数: 113

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