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A guide for kernel generalized regression methods for genomic-enabled prediction
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DOI：10.1038/s41437-021-00412-1.png)
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摘要
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The primary objective of this paper is to provide a guide on implementing Bayesian generalized kernel regression methods for genomic prediction in the statistical software R. Such methods are quite efficient for capturing complex non-linear patterns that conventional linear regression models cannot. Furthermore, these methods are also powerful for leveraging environmental covariates, such as genotype x environment (GxE) prediction, among others. In this study we provide the building process of seven kernel methods: linear, polynomial, sigmoid, Gaussian, Exponential, Arc-cosine 1 and Arc-cosine L. Additionally, we highlight illustrative examples for implementing exact kernel methods for genomic prediction under a single-environment, a multi-environment and multi-trait framework, as well as for the implementation of sparse kernel methods under a multi-environment framework. These examples are followed by a discussion on the strengths and limitations of kernel methods and, subsequently by conclusions about the main contributions of this paper.
Keyword:
LINEAR UNBIASED PREDICTION
GENETIC VALUES
QUANTITATIVE TRAITS
ASSISTED PREDICTION
EPISTASIS
MODELS
HERITABILITY
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被引数:
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