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DOI：10.1016/j.survophthal.2022.08.001.png)
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An 8-year-old boy presented with acute visual loss in the right eye and nausea, vomiting, and diplopia. Imaging revealed a right orbital apex mass. Biopsy showed Langerhans cell histiocytosis (LCH), and the patient was diagnosed with isolated orbital LCH causing an or-bital apex syndrome. A 12-month cytarabine chemotherapy course was begun, during which the patient developed bilateral optic disc edema. He was diagnosed with cytarabine-induced intracranial hypertension, which was successfully treated with acetazolamide. The cytara-bine course was completed with complete resolution of the LCH lesion. The ophthalmologic relevance of this rare disorder is discussed.& COPY; 2022 Elsevier Inc. All rights reserved.
Keyword:
Langerhans cell histiocytosis (LCH)
Orbital apex syndrome
Cytarabine
Intracranial hypertension
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ANNALS OF HEMATOLOGY
ANNALS OF HEMATOLOGYIF2.4
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