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A highly accessible copper single-atom catalyst for wound antibacterial application
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DOI：10.1007/s12274-021-3432-x.png)
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Abstract
En 中文
Bacterial infection arised from multipathogenic bacteria is a tricky issue that attracts worldwide attentions. In this paper, a highly accessible copper single-atom catalyst (Cu SAC) supported by biocompatible N-doped mesoporous carbon nanospheres was synthesized with the emulsion-template method. The tightly anchored copper single-atom of the catalyst could effectively transform O-2 into O-2(-center dot) under ambient conditions by the ultra-large pore size (similar to 23.80 nm) and small particle size (similar to 97.71 nm). Due to multiple synergistically oxidative damages to biomolecules, the Cu SAC could be employed to eliminate different bacteria in vitro without the generation of multidrug resistance (MDR). Moreover, the Cu SAC could also promote wound healing in vivo by eradicating the propagation of bacteria at wound. It is envisioned that the Cu SAC with superior antibacterial performance could be applied in the treatment of related bacterial infection in future.y
Keywords:
copper single-atom catalyst
mesoporous carbon nanospheres
catalytic transformation of oxygen
oxidative stress
bacterial infection healing
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