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A protein-DNA docking benchmark
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DOI：10.1093/nar/gkn386.png)
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摘要
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We present a protein-DNA docking benchmark containing 47 unbound-unbound test cases of which 13 are classified as easy, 22 as intermediate and 12 as difficult cases. The latter shows considerable structural rearrangement upon complex formation. DNA-specific modifications such as flipped out bases and base modifications are included. The benchmark covers all major groups of DNA-binding proteins according to the classification of Luscombe et al., except for the zipper-type group. The variety in test cases make this non-redundant benchmark a useful tool for comparison and development of protein-DNA docking methods. The benchmark is freely available as download from the internet.
Keyword:
INFORMATION
HADDOCK
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期刊
IF:
13.1
论文数:
3.6W
被引数:
29.0W
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引用论文
Information-driven protein-DNA docking using HADDOCK: it is a matter of flexibility.png)
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