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A voltage-dependent switch underlies efficient yet specific learning and memory
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DOI：10.1016/j.cub.2026.01.014.png)
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摘要
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• mAChR-B, which prevents non-specific learning, interferes with efficient learning • mAChR-B is voltage dependent and shifts to a low-activity state at depolarization • Active Kenyon cells, where learning occurs, shift mAChR-B to a low-activity state • mAChR-B shift to a low-activity state allows for efficient learning to occur
Keyword:
GPCRs
Drosophila
voltage-dependent
learning
muscarinic receptors
mAChR-B
memory
specificity
accuracy
mushroom body
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期刊
IF:
7.5
论文数:
2.2W
被引数:
7.8W
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