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A wirelessly powered, light-controlled, bioresorbable stimulation system with programmable polyphasic waveforms

delete2026-06-16
delete0
PRE
AI
J
Jong Uk Kim
S
Seung Gi Seo
H
Hongkai Wang
E
Eric Rytkin
J
Jiarui Gong
周杰 封面图
周杰 (Jie Zhou)
J
Junhwan Choi
J
Jiwon Kim
S
Sun Young Park
A
Anna Pfenniger
R
Rishi K. Arora
A
Aleksei Mikhailov
J
Jinheon Jeong
S
Seungyeob Kim
Y
Yamin Zhang
R
Ravi F. Nuxoll
H
Hak‐Young Ahn
G
Geumbee Lee
S
Shupeng Li
D
Dae‐Hyeon Song
S
Sangwon Cha
Y
Young Jin Jo
S
Sang Min Won
T
Tae‐il Kim
Y
Yei Hwan Jung
S
Sumanas W. Jordan
Yonggang Huang 封面图
Yonggang Huang (Yonggang Huang)
J
Jae‐Young Yoo *
I
Igor R. Efimov *
C
Colin K. Franz *
Z
Zhenqiang Ma *
S
Sung Hun Jin *
J
John A. Rogers *
DOI：10.1038/s41928-026-01655-8delete
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摘要

摘要

En 中文
无线生物可吸收系统可用于电刺激，能在临床上相关的时间范围内输送电疗法，随后以无害的方式溶解。此类系统先前已用于神经再生和心脏起搏，向目标部位输送单相脉冲。本文报道了一种无线供电系统，可通过组织穿透近红外光对刺激波形进行程序控制。该技术依赖于一种生物可吸收的硅光电晶体管，其设计用于光学调制电路中关键节点的电流。我们证明该方法可对刺激脉冲实现精确控制——允许向单个或多个部位输送单相、双相和多相波形——且所有能量均无线输送至单一接收单元。通过小型和大型动物模型，我们进一步证明该技术可进行单腔和双腔心脏起搏，以及用于诱导和阻断膈肌运动的膈神经肌肉刺激。利用生物可吸收的硅光电晶体管光学调制电路中的电流，可创建一种无线供电的刺激系统，该系统可利用组织穿透近红外光对刺激波形进行程序控制。

期刊

Nature Electronics 封面图
Nature Electronics
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40.9
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1.7K
被引数:
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hanyang university
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university of chicago
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university of wisconsin-madison
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Korea Advanced Institute of Science and Technology
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sungkyunkwan university
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A
abilitylab
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49
论文数: 18
被引数: 0
K
Kyung Hee University
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Northwestern University
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