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A zwitterionic twist

delete2024-09-23
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PRE
AI
S
Sihan Xiong
K
Khalid Shah *
C
Chuang LIU *
DOI:10.1038/s41570-024-00654-7delete
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摘要

摘要

En 中文
An mRNA sequence that encodes a zwitterionic polypeptide fused to a therapeutic protein improves the pharmacokinetic properties of mRNA therapeutics.

期刊

Nature Reviews Chemistry 封面图
Nature Reviews Chemistry
IF:
51.7
论文数:
1.0K
被引数:
1.6W

机构

H
Harvard University
学者数:
26.5W
论文数: 22.0W
被引数: 28.7W
H
Harvard Medical School
学者数:
6.5W
论文数: 4.8W
被引数: 91
引用论文

引用论文

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A De Novo Strategy To Improve Pharmacokinetics of Proteins from mRNA Therapeutics via Zwitterionic Polypeptide Fusion
err2024-07-29
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errLuozhong, Sijin; Li, Ruoxin; Zhen, Tian; Cao, Zeyu; Dani, Bhashyam; Zhang, Prince; Mcilhenny, Kay; Fang, Liang; Mcmullen, Patrick; Jiang, Shaoyi
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