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Absorbable cyst brushes

delete2023-08-23
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AI
F
Filipe Marques
W
Wouter van der Wijngaart
N
Niclas Roxhed *
DOI:10.1007/s10544-023-00674-ydelete
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摘要

摘要

En 中文
Cytobrushes are used for low-invasive sample collection and screening in multiple diseases, with a significant impact on early detection, prevention, and diagnosis. This study focuses on improving the safety of cell brushing in hard-to-reach locations by exploring brush construction from absorbable materials. We investigated the efficacy of loop brushes made of absorbable suture wires of Chirlac, Chirasorb, Monocryl, PDS II, Vicryl Rapid, Glycolon, and Catgut during their operation in conjunction with fine-needle aspiration in an artificial cyst model. PDS II brushes demonstrated the highest efficiency, while Monocryl and Catgut also provided a significant brushing effect. Efficient brushes portrayed higher flexural rigidity than their counterparts, and their efficiency was inversely proportional to their plastic deformation by the needle. Our results open avenues for safer cell biopsies in hard-to-reach locations by utilizing brushes composed of absorbable materials.
Keyword:
Cancer
Cysts
Diagnostics
Cell biopsy
Cell brush
Loop brush
Absorbable materials
Fine Needle Aspiration
Endoscopic Ultrasound
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期刊

Biomedical Microdevices 封面图
Biomedical Microdevices
IF:
3.3
论文数:
2.1K
被引数:
3.4K

机构

R
Royal Institute of Technology
学者数:
1.8W
论文数: 1.8W
被引数: 25
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