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Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design

delete2023-07-26
delete45
delete
OA
AI
Y
Yang Li
N
Nan Li
刘伟 封面图
刘伟 (Wei Liu)
A
Aleksander Promiński
S
Seoung‐Hun Kang
Y
Yahao Dai
Y
Youdi Liu
胡华伟 封面图
胡华伟 (Huawei Hu)
S
Shinya Wai
S
Shilei Dai
Z
Zhe Cheng
Q
Qi Su
P
Ping Kwong Cheng
W
Wei Chen
L
Lihua Jin
J
Jeffrey A. Hubbell
B
Bozhi Tian
S
Sihong Wang *
DOI:10.1038/s41467-023-40191-3delete
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摘要

摘要

En 中文
Stretchable electronics are attractive for a range of biomedical applications, but are challenging to prepare with suitable mechanical properties. Here, the authors report the use of a soft interlayer that allows the development of stretchable electronics with tissue-like material properties. Soft and stretchable electronics have emerged as highly promising tools for biomedical diagnosis and biological studies, as they interface intimately with the human body and other biological systems. Most stretchable electronic materials and devices, however, still have Young's moduli orders of magnitude higher than soft bio-tissues, which limit their conformability and long-term biocompatibility. Here, we present a design strategy of soft interlayer for allowing the use of existing stretchable materials of relatively high moduli to versatilely realize stretchable devices with ultralow tissue-level moduli. We have demonstrated stretchable transistor arrays and active-matrix circuits with moduli below 10 kPa-over two orders of magnitude lower than the current state of the art. Benefiting from the increased conformability to irregular and dynamic surfaces, the ultrasoft device created with the soft interlayer design realizes electrophysiological recording on an isolated heart with high adaptability, spatial stability, and minimal influence on ventricle pressure. In vivo biocompatibility tests also demonstrate the benefit of suppressing foreign-body responses for long-term implantation. With its general applicability to diverse materials and devices, this soft-interlayer design overcomes the material-level limitation for imparting tissue-level softness to a variety of bioelectronic devices.
Keyword:
POLYMER
FILMS
INTERFACES
STABILITY
FRACTURE
WORK
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期刊

Nature Communications 封面图
Nature Communications
IF:
15.7
论文数:
9.4W
被引数:
91.2W

机构

U
university of chicago
学者数:
4.5W
论文数: 3.7W
被引数: 80
University of California System 封面图
University of California System
学者数:
37.7W
论文数: 33.8W
被引数: 6.6K
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