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Activating transcription factor 3 aggravates renal fibrosis by regulating EGR2-mediated autophagy

delete2026-07-01
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PRE
AI
R
Ruiwei Yan
A
Anni Song
M
Mingcun Hu
X
Xingjie Yin
W
Wei Xiong
P
Pan Gao
张纯 cover
张纯 (Chun Zhang) *
DOI：10.1016/j.trsl.2026.06.022delete
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Abstract

Abstract

En 中文
Chronic kidney disease (CKD) affects approximately 10% of global populations, pathologically characterized by renal fibrosis including extracellular matrix (ECM) deposition and renal tubular atrophy. Emerging evidence suggests that autophagy plays a crucial role in renal fibrosis, but the regulatory mechanisms are still not well understood.

Journal

Translational Research cover
Translational Research
IF:
5.9
Papers:
2.0K
Citations:
7.1K

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