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'Activity-silent' working memory in prefrontal cortex: a dynamic coding framework
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DOI：10.1016/j.tics.2015.05.004.png)
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摘要
En 中文
Working memory (WM) provides the functional backbone to high-level cognition. Maintenance in WM is often assumed to depend on the stationary persistence of neural activity patterns that represent memory content. However, accumulating evidence suggests that persistent delay activity does not always accompany WM maintenance but instead seems to wax and wane as a function of the current task relevance of memoranda. Furthermore, new methods for measuring and analysing population-level patterns show that activity states are highly dynamic. At first glance, these dynamics seem at odds with the very nature of WM. How can we keep a stable thought in mind while brain activity is constantly changing? This review considers how neural dynamics might be functionally important for WM maintenance.
Keyword:
SHORT-TERM-MEMORY
INFERIOR TEMPORAL CORTEX
EARLY VISUAL-CORTEX
NEURAL MECHANISMS
ATTENTIONAL TEMPLATES
DELAYED-ALTERNATION
PERSISTENT ACTIVITY
COGNITIVE CONTROL
NETWORK DYNAMICS
DECISION-MAKING
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IF:
17.2
论文数:
3.6K
被引数:
3.5W
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Synaptic reverberation underlying mnemonic persistent activity助眠持续活动的突触混响.png)
TRENDS IN NEUROSCIENCES
TRENDS IN NEUROSCIENCESIF15.1
PREAI
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