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Advancing Heart Ageing in Ischemic Heart Disease: Insights from CMR and ECG Analysis

delete2026-07-17
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OA
AI
A
Ahmed M Salih *
E
Elisa Rauseo *
I
Ilaria Boscolo Galazzo
E
Esmeralda Ruiz Pujadas
V
Víctor M. Campello
K
Karim Lekadir
N
Nay Aung
G
Greg Slabaugh
G
Ghaith Sharaf Dabbagh
C
C. Anwar A. Chahal
G
Gloria Menegaz
S
Steffen E. Petersen
DOI:10.1016/j.jocmr.2026.102776delete
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Abstract

Abstract

En 中文
Ischemic heart disease (IHD) patients undergo cardiovascular alterations that can accelerate heart ageing. Estimating biological heart age using advanced cardiac magnetic resonance (CMR) and electrocardiogram (ECG)-derived phenotypes provides a biomarker for heart ageing. We investigated the relationship of IHD and heart ageing using biological age estimation biomarkers, and the contribution of conventional cardiac imaging indices and vascular risk factors (VRFs).
Keywords:
BMI
Body mass index
CMR
Cardiac magnetic resonance
CVDs
Cardiovascular diseases
ECG
Electrocardiogram
ED
End diastole
ES
End systolic
HAG
Heart age gap
IHD
Ischemic heart disease
LV
Left ventricle
MYO
Myocardium
PCA
Principal Component Analysis
RV
Right ventricle
UKB
UK Biobank
VRFs
Vascular risk factors
Heart age
ischemic heart disease
cardiac magnetic resonance
vascular risk factors
ECG
radiomics
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Journal

Journal of Cardiovascular Magnetic Resonance cover
Journal of Cardiovascular Magnetic Resonance
IF:
6.1
Papers:
2.3K
Citations:
6.9K

Organization

Q
Queen Mary University of London
Scholars:
947
Papers: 467
Citations: 3.4W
WellSpan Health cover
WellSpan Health
Scholars:
23
Papers: 20
Citations: 103
D
department of mathematics and computer science
Scholars:
167
Papers: 98
Citations: 0
U
university of verona
Scholars:
2.2K
Papers: 890
Citations: 0
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