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Aerobic biodegradation of cefpirome sulfate by Sphingomonas melonis P33: Performance, pathways, and genomic characterization

delete2026-08-04
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PRE
AI
Y
Yuyang Wang
H
Hongchao Min
Q
Qi Wang
T
Tingting Zhang
Y
Yin Li
J
Jiayu Zhang
L
Lin Lin
X
Xiaoyan Li
B
Bing Li *
DOI:10.1016/j.jwpe.2026.110672delete
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Abstract

Abstract

En 中文
• Sphingomonas sp. P33 can utilize cefpirome as sole carbon, nitrogen and energy source • Strain P33 shows broad substrate spectrum with adaptation to wastewater condition • Four degradation pathways consisting of products with lower ecotoxicity are established • Whole genome sequencing reveals genes for modifying cephem nucleus and side chains
Keywords:
Fourth-generation cephalosporins
Sphingomonas melonis
Biodegradation mechanisms
Genomics
Ecotoxicity

Journal

Journal of Water Process Engineering cover
Journal of Water Process Engineering
IF:
6.7
Papers:
1.0W
Citations:
3.3W

Organization

T
tsinghua university
Scholars:
11.5W
Papers: 9.9W
Citations: 137
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