.png){kind=icon}
返回
Ag2S quantum dot theragnostics
.png){kind=icon}
PRE
AI
DOI：10.1039/d0bm01576h.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Silver sulfide quantum dots (Ag2S QDs) as a theragnostic agent have received much attention because they provide excellent optical and chemical properties to facilitate diagnosis and therapy simultaneously. Ag2S QDs possess brightness and photostability suitable for intense and stable bioimaging. It has been verified via in vitro and in vivo studies that Ag2S QDs do not cause serious toxicity, unlike the first generation of widely used heavy metal-based (cadmium or lead) QDs. In particular, Ag2S QDs emit in the near infrared-II region (NIR-II window) that enables deep tissue penetration and imaging. Furthermore, various chemotherapeutic agents and targeting moieties can be efficiently conjugated to the surface of Ag2S QDs due to advanced technologies in the relevant surface chemistry using covalent bonding, high affinity, and electrostatic interaction. In addition, Ag2S QDs themselves exhibit an anticancer activity based on the photothermal effect. Consequently, Ag2S QDs can function as both a therapeutic agent and an imaging agent in imaging-based diagnosis concurrently, which led to the creation of Ag2S theragnostic nanomaterials. In this review, the synthetic methods, physicochemical properties, bioconjugations, and bioapplications of Ag2S QD theragnostic nanomaterials are discussed in detail.
Keyword:
VIVO REAL-TIME
HIGHLY LUMINESCENT
CADMIUM
MULTICOLOR
THERAPY
BRIGHT
SIZE
NANOPARTICLES
NANOMATERIALS
VISUALIZATION
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
5.7
论文数:
4.8K
被引数:
2.1W
机构
引用论文
In Vivo Fluorescence Imaging with Ag2S Quantum Dots in the Second Near-Infrared RegionAg2S量子点在第二近红外区的体内荧光成像
PREAI
分享收藏Biodistribution, pharmacokinetics and toxicology of Ag2S near-infrared quantum dots in mice.png)
BIOMATERIALS
BIOMATERIALSIF12.9
PREAI
分享收藏Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared WindowACS NANO
OAAI
ACS NANOIF16
OAAI分享收藏Water-soluble Ag2S quantum dots for near-infrared fluorescence imaging in vivoBIOMATERIALS
BIOMATERIALSIF12.9
PREAI
分享收藏InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and BiocompatibleInAs/InP/ZnSe核/壳量子点作为近红外发射器: 明亮，窄带，不含镉和生物相容性OAAI
OAAI分享收藏
查看更多内容