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Age-dependent variations in circulating Tfh and Tfr cells following SARS-CoV-2 infection
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DOI：10.1016/j.imlet.2026.107176.png)
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Abstract
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• Ratio cTfh/cTfr was decreased in children compared to adults nine months after infection. • The proportion of anti-spike-RBD IgG responders prevailed in children. • The majority of adults manifested positive anti-SARS-CoV-2 specific T cell responses.
Keywords:
Follicular helper cells
follicular regulatory T cells
ICOS
specific antibodies
pediatric patients
B cells
FOXP3
Tregs
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