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Aging reduces neural specialization in ventral visual cortex

delete2004-08-20
delete526
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OA
AI
D
Denise C. Park
T
Thad A. Polk
R
Rob Park
M
Meredith Minear
A
Anna E. Savage
S
Smith, MR
DOI:10.1073/pnas.0405148101delete
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摘要

摘要

En 中文
The present study investigated whether neural structures become less functionally differentiated and specialized with age. We studied ventral visual cortex, an area of the brain that responds selectively to visual categories (faces, places, and words) in young adults, and that shows little atrophy with age. Functional MRI was used to estimate neural activity in this cortical area, while young and old adults viewed faces, houses, pseudowords, and chairs. The results demonstrated significantly less neural specialization for these stimulus categories in older adults across a range of analyses.
Keyword:
AGE-RELATED-CHANGES
HUMAN EXTRASTRIATE CORTEX
FUSIFORM FACE AREA
ADULT LIFE-SPAN
PROCESSING-SPEED
FUNCTIONAL MRI
OLDER ADULTS
ACTIVATION
COGNITION
MEMORY
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P
Proceedings of the National Academy of Sciences of the United States of America
IF:
9.1
论文数:
10.8W
被引数:
73.5W

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