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Amygdala and hippocampal volumes as neural correlates of resilience and loneliness in older adults
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DOI：10.1016/j.neurobiolaging.2026.06.011.png)
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Abstract
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• First study to link medial temporal lobe structure with resilience in older adults. • Larger amygdala and hippocampal volumes were associated with higher resilience. • Larger amygdala volume was associated with lower loneliness during COVID-19. • Females showed greater loneliness and lower resilience than males. • Hypothesis-generating evidence for neural targets to enhance resilience in late-life.
Keywords:
Aging
Resilience
Loneliness
Amygdala
Hippocampus
Medial temporal lobe
Magnetic Resonance Imaging (MRI)
Social isolation
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