.png){kind=icon}
返回
Analysing gene function after duplication
.png){kind=icon}
OA
AI
DOI：10.1002/bies.1128.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
After gene duplication, mutations cause the gene copies to diverge. The classical model predicts that these mutations will generally lead to the loss of function of one gene copy; rarely, new functions will be created and both duplicate genes are conserved. In contrast, under the subfunctionalization model both duplicates are preserved due to the partition of different functions between the duplicates. A recent study((l)) provides support for the subfunctionalization model, identifying several expressed gene duplicates common to humans and mice that contain regions conserved in one duplicate but variable in the other (and vice versa). We discuss both the methodology used in this study and also how gene phylogeny may lead to additional evidence for the importance of subfunctionalization in the evolution of new genes. (C) 2001 John Wiley & Sons, Inc.
Keyword:
EVOLUTION
GENOME
PRESERVATION
DIVERGENCE
REGIONS
ACID
FATE
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
2.7
论文数:
4.7K
被引数:
1.0W
机构
暂无机构信息
引用论文
分享收藏Complex arrangement of genes within a 220-kb region of double-duplicated DNA on human 2q37.1.png)
GENOMICS
GENOMICSIF3
PREAI
分享收藏分享收藏分享收藏
查看更多内容