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Anti-inflammatory role of linden (Tilia spp.) honey in LPS-induced RAW264.7 cells and mouse model of acute lung injury
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DOI：10.1016/j.jff.2026.107384.png)
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Abstract
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• Linden honey (LH) effectively alleviates LPS-induced acute lung injury (ALI) in mice • LH suppresses TLR4/NF-κB signaling pathway in both macrophages and lung tissue • LH administration reduces pulmonary edema and inflammatory cell infiltration • LH represents a promising natural therapeutic candidate for preventing inflammatory lung diseases
Keywords:
Acute lung injury
Linden honey
Lipopolysaccharide
RAW264.7 macrophages
TLR4/NF-κB signaling
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