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ARID1A terminates gastric regeneration to prevent cancer

delete2026-06-30
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PRE
AI
A
Adrian K.H. Loe
A
Alyssa Ialongo
Y
Yan Qin
A
Amin Afkhami-Poostchi
S
Shaheed W. Hakim
C
Chiyeol Choi
M
Motonobu Saito
H
Haiyang Guo
H
Ho Sung Rhee *
T
Tae-Hee Kim *
DOI：10.1016/j.devcel.2026.06.002delete
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Abstract

Abstract

En 中文
• Gastric recovery after injury involves chromatin re-opening • ARID1A is required for gastric tissue recovery • ARID1A recruits lineage-specific transcription factors to activate recovery genes • Impaired recovery increases vulnerability to cancer

Journal

Developmental Cell cover
Developmental Cell
IF:
8.7
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6.3K
Citations:
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Unity Health Toronto
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