logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回

Artificial intelligence in diagnostics-a pathology perspective

delete2025-10-01
delete0
PRE
AI
S
Stefan Schulz
M
Moritz Jesinghaus
S
Sebastian Foersch *
DOI：10.1007/s00761-025-01849-3delete
delete原文链接
delete原文求助
delete分享
delete收藏
摘要

摘要

En 中文
肿瘤诊断和治疗日益增长的复杂性与个性化趋势，为病理学带来了新的挑战。与此同时，人工智能（AI）正从未来的概念发展为数字医学的核心领域。随着数字全切片图像（WSIs）的可用性以及日益强大的深度学习架构的出现，自2019年左右以来，数字病理学领域的出版物数量几乎呈指数级增长。在算法层面，近年来涌现了诸多创新：最初主导该领域的卷积神经网络（CNNs）正逐渐被基于视觉Transformer（ViT）的模型所取代。自2023年以来，基础模型因其广泛适用性和泛化能力而迅速获得重要性。概念验证研究已反复证明，基于AI的解决方案能够提升诊断工作流程的效率与敏感性。多个用于组织病理学的AI算法已获得美国和欧洲监管机构的批准。更近期的进展，如视觉-语言模型（VLMs），能够实现文本和图像数据的跨模态整合，为诊断开辟了新的交互可能性。总体而言，该领域正从概念验证研究转向临床实施。特别是，基础模型有望在不久的将来从根本上重塑组织病理诊断的结构。然而，在实现广泛临床应用之前，仍需克服技术、法律和社会心理层面的障碍。
Keyword:
Digital pathology
Artificial intelligence in pathology
Diagnostic artificial intelligence biomarkers
Digital transformation
Pattern recognition
Decision support
Multimodal data integration
Digital pathology
Artificial intelligence in pathology
Diagnostic artificial intelligence biomarkers
Digital transformation
Pattern recognition
Decision support
Multimodal data integration

期刊

O
Onkologie
IF:
0.2
论文数:
141
被引数:
218

机构

P
Philipps University Marburg
学者数:
1.3W
论文数: 1.0W
被引数: 10
J
johannes gutenberg university of mainz
学者数:
905
论文数: 358
被引数: 0
引用论文

引用论文

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer深度学习可以直接从胃肠道肿瘤的组织学中预测微卫星不稳定性
errNATURE MEDICINE
IF50
err2019-06-03
err761
errOAAI
errKather, Jakob Nikolas; Pearson, Alexander T.; Halama, Niels; Jaeger, Dirk; Krause, Jeremias; Loosen, Sven H.; Marx, Alexander; Boor, Peter; Tacke, Frank; Neumann, Ulf Peter; Grabsch, Heike I.; Yoshikawa, Takaki; Brenner, Hermann; Chang-Claude, Jenny; Hoffmeister, Michael; Trautwein, Christian; Luedde, Tom
err分享
err收藏
A multimodal generative AI copilot for human pathology用于人类病理学的多模态生成AI副驾驶
errNature
IF0
err2024-06-12
err0
errOAAI
errMing Y. Lu; Bowen Chen; Drew F. K. Williamson; Richard J. Chen; Melissa Zhao; Aaron K. Chow; Kenji Ikemura; Ahrong Kim; Dimitra Pouli; Ankush Patel; Amr Soliman; Chengkuan Chen; Tong Ding; Judy J. Wang; Georg Gerber; Ivy Liang; Long Phi Le; Anil V. Parwani; Luca L. Weishaupt; Faisal Mahmood
err分享
err收藏
Artificial intelligence-based digital pathology using H&E-stained whole slide images in immuno-oncology: from immune biomarker detection to immunotherapy response prediction基于人工智能的数字病理学在免疫肿瘤学中的应用：从免疫生物标志物检测到免疫治疗反应预测（使用H&E染色的全切片图像）
err
IF0
err
err0
PREAI
err
err分享
err收藏
Prompt injection attacks on vision language models in oncology肿瘤学中视觉语言模型的提示注入攻击
errNATURE COMMUNICATIONS
IF15.7
err2025-02-01
err1
errOAAI
errClusmann, Jan; Ferber, Dyke; Wiest, Isabella C.; Schneider, Carolin V.; Brinker, Titus J.; Foersch, Sebastian; Truhn, Daniel
err分享
err收藏
From whole-slide image to biomarker prediction: end-to-end weakly supervised deep learning in computational pathology从全切片图像到生物标志物预测: 计算病理学中的端到端弱监督深度学习
errNATURE PROTOCOLS
IF16
err2024-09-16
err2
PREAI
errEl Nahhas, Omar S. M.; van Treeck, Marko; Woelflein, Georg; Unger, Michaela; Ligero, Marta; Lenz, Tim; Wagner, Sophia J.; Hewitt, Katherine J.; Khader, Firas; Foersch, Sebastian; Truhn, Daniel; Kather, Jakob Nikolas
err分享
err收藏
Artificial Intelligence Helps Pathologists Increase Diagnostic Accuracy and Efficiency in the Detection of Breast Cancer Lymph Node Metastases人工智能帮助病理学家提高在乳腺癌症淋巴结转移检测中的诊断准确性和效率
errAmerican Journal of Surgical Pathology
IF0
err2024-05-27
err0
errOAAI
errJuan Antonio Retamero; Emre Gulturk; Alican Bozkurt; Sandy Liu; Maria Gorgan; Luis Moral; Margaret Horton; Andrea Parke; Kasper Malfroid; Jill Sue; Brandon Rothrock; Gerard Oakley; George DeMuth; Ewan Millar; Thomas J. Fuchs; David S. Klimstra
err分享
err收藏
Global research trends and foci of artificial intelligence-based tumor pathology: a scientometric study
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2022-09-06
err42
errOAAI
errShen, Zefeng; Hu, Jintao; Wu, Haiyang; Chen, Zeshi; Wu, Weixia; Lin, Junyi; Xu, Zixin; Kong, Jianqiu; Lin, Tianxin
err分享
err收藏
A foundation model for clinical-grade computational pathology and rare cancers detection临床级计算病理学和罕见癌症检测的基础模型
errNATURE MEDICINE
IF50
err2024-07-22
err7
errOAAI
errVorontsov, Eugene; Bozkurt, Alican; Casson, Adam; Shaikovski, George; Zelechowski, Michal; Severson, Kristen; Zimmermann, Eric; Hall, James; Tenenholtz, Neil; Fusi, Nicolo; Yang, Ellen; Mathieu, Philippe; van Eck, Alexander; Lee, Donghun; Viret, Julian; Robert, Eric; Wang, Yi Kan; Kunz, Jeremy D.; Lee, Matthew C. H.; Bernhard, Jan H.; Godrich, Ran A.; Oakley, Gerard; Millar, Ewan; Hanna, Matthew; Wen, Hannah; Retamero, Juan A.; Moye, William A.; Yousfi, Razik; Kanan, Christopher; Klimstra, David S.; Rothrock, Brandon; Liu, Siqi; Fuchs, Thomas J.
err分享
err收藏
Deep learning for diagnosis and survival prediction in soft tissue sarcoma深度学习在软组织肉瘤诊断和生存预测中的应用
errANNALS OF ONCOLOGY
IF65.4
err2021-09-01
err57
errOAAI
errFoersch, S.; Eckstein, M.; Wagner, D-C; Gach, F.; Woerl, A-C; Geiger, J.; Glasner, C.; Schelbert, S.; Schulz, S.; Porubsky, S.; Kreft, A.; Hartmann, A.; Agaimy, A.; Roth, W.
err分享
err收藏
A comprehensive evaluation of histopathology foundation models for ovarian cancer subtype classification卵巢癌亚型分类中组织病理学基础模型的全面评估
errNPJ PRECISION ONCOLOGY
IF8
err2025-01-30
err0
errOAAI
errBreen, Jack; Allen, Katie; Godson, Lucy; Orsi, Nicolas M.; Ravikumar, Nishant
err分享
err收藏
学者 查看更多内容