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Asparagusic acid
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DOI：10.1016/j.phytochem.2013.09.014.png)
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Asparagusic acid (1,2-dithiolane-4-carboxylic acid) is a simple sulphur-containing 5-membered heterocyclic compound that appears unique to asparagus, though other dithiolane derivatives have been identified in non-food species. This molecule, apparently innocuous toxicologically to man, is the most probable culprit responsible for the curious excretion of odorous urine following asparagus ingestion. The presence of the two adjacent sulphur atoms leads to an enhanced chemical reactivity, endowing it with biological properties including the ability to substitute potentially for alpha-lipoic acid in alpha-keto-acid oxidation systems. This brief review collects the scattered data available in the literature concerning asparagusic acid and highlights its properties, intermediary metabolism and exploratory applications. (C) 2013 Elsevier Ltd. All rights reserved.
Keyword:
Asparagus
Asparagus officinalis L.
Asparagaceae family
Asparagusic acid
1,2-Dithiolane-4-carboxylic acid
Sulphur heterocycle
Urine odour
Short review
期刊
IF:
3.4
论文数:
1.3W
被引数:
3.2W
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