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Assembling the pieces

delete2008-03-01
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OA
AI
D
Dennis J. Thiele *
J
Jonathan D. Gitlin
DOI:10.1038/nchembio0308-145delete
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摘要

摘要

En 中文
Transition metals function as cofactors in specific proteins, catalyzing electron exchange reactions, binding substrates and stabilizing protein structure. Studies of human diseases and of model organisms have defined many of the molecular details of metal uptake, trafficking, and excretion. The current challenge is to integrate these details into a systematic view of metal content, speciation, localization and use within organisms and ecosystems.
Keyword:
RAY-FLUORESCENCE MICROSCOPY
COPPER
IRON
METABOLISM
HOMEOSTASIS
TOPOGRAPHY
EVOLUTION
VIRULENCE
NUTRIENT
ELEMENTS
AI总结

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期刊

Nature Chemical Biology 封面图
Nature Chemical Biology
IF:
13.7
论文数:
4.8K
被引数:
3.3W

机构

D
Duke University
学者数:
6.3W
论文数: 5.7W
被引数: 6.5W
W
washington university (wustl)
学者数:
5.5W
论文数: 4.5W
被引数: 70
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