Association of a Digital Clinical Decision Support Platform With Early Outcomes After Pediatric Allogeneic Hematopoietic Cell Transplantation: A Three-Era Guideline Implementation Cohort Study

2026-06-19

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Kanayo Nwankwo *

Elizabeth Klein

Eric Leroux

Binni Kunvarjee

Jaap Jan Boelens

Maria Cancio

DOI：10.1016/j.jtct.2026.06.026

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• Sustained adoption was associated with shorter inpatient LOS • NRM showed a lower adjusted competing-risk signal after sustained use • Use concentrated in HCT, infection, GVHD, and supportive care • ICU use, readmissions, and survival were not adversely affected • Prospective studies should measure exposure and adherence

Association of a Digital Clinical Decision Support Platform With Early Outcomes After Pediatric Allogeneic Hematopoietic Cell Transplantation: A Three-Era Guideline Implementation Cohort Study

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