Contextual Factors Influencing Teachers’ Familiarity with and Perceptions of 4IR Technologies in Nigerian Secondary Schools

Chidubem Deborah Adamu

doi:10.3390/educsci16081290

Association of Small Dense LDL Cholesterol and Inflammation with Plaque Rupture in Acute Coronary Syndrome: An OCT Study

2026-06-12

0

PRE

AI

K

Kengo Suzuki

T

Teruo Sekimoto *

S

Shinji Koba

T

Taito Arai

H

Hiroyoshi Mori

K

Koshiro Sakai

H

Hiroki Tanisawa

R

Rikuo Sakai

H

Hideaki Tanaka

M

Masashi Katagiri

S

Shiori Fuse

T

Tomonori Yamashita

Y

Yosuke Oishi

K

Kunihiro Ogura

R

Ryota Kosaki

H

Hiroaki Tsujita

S

Seita Kondo

T

Toshiro Shinke

DOI：10.1016/j.jacl.2026.06.007

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Abstract

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• Elevated sd-LDL-C is independently associated with the presence of OCT-defined PR in the culprit lesion of patients with acute coronary syndrome. • Higher quartiles of sd-LDL-C are persistently associated with PR even after multivariable adjustment, independent of LDL-C levels. • The co-existence of high sd-LDL-C and high hs-CRP is associated with a higher frequency of PR in the culprit lesion, representing the additive impact of lipid quality and systemic inflammation on plaque morphology. • OCT-defined morphological features of plaque vulnerability, such as thin-cap fibroatheroma, are more prevalent in the culprit lesions of patients with elevated sd-LDL-C and hs-CRP.

Association of Small Dense LDL Cholesterol and Inflammation with Plaque Rupture in Acute Coronary Syndrome: An OCT Study

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