.png){kind=icon}
返回
Astrocyte morphology
.png){kind=icon}
OA
AI
DOI：10.1016/j.tcb.2023.09.006.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal feature of astrocytes is their complex and visually enchanting morphology, referred to as bushy, spongy, and star-like. A central precept of this review is that such complex morphological shapes evolved to allow astrocytes to contact and signal with diverse cells at a range of distances in order to sample, regulate, and contribute to the extracellular milieu, and thus participate widely in cell-cell signaling during physiology and disease. The recent use of improved imaging methods and cell-specific molecular evaluations has revealed new information on the structural organization and molecular underpinnings of astrocyte morphology, the mechanisms of astrocyte morphogenesis, and the contributions to disease states of reduced morphology. These insights have reignited interest in astrocyte morphological complexity as a cornerstone of fundamental glial biology and as a critical substrate for multicellular spatial and physiological interactions in the CNS.
Keyword:
3-DIMENSIONAL RELATIONSHIPS
PERISYNAPTIC ASTROGLIA
CALCIUM SIGNALS
PLASTICITY
GLIA
DOMAINS
MODEL
MORPHOGENESIS
ORGANIZATION
PHYSIOLOGY
期刊
IF:
18.1
论文数:
3.1K
被引数:
2.0W
机构
引用论文
Reviewing the Exergy Analysis of Solar Thermal Systems Integrated with Phase Change Materials.png)
EnergiesOAAI
EnergiesIF0
OAAI分享收藏Designing Model for Calculating the Amount of Cyber Risk Insurance2017 Fourth International Conference on Mathematics and Computers in Sciences and in Industry (MCSI)
2017 Fourth International Conference on Mathematics and Computers in Sciences and in Industry (MCSI)IF0
PREAI
分享收藏分享收藏Organizing principles of astrocytic nanoarchitecture in the mouse cerebral cortexCURRENT BIOLOGY
OAAI
CURRENT BIOLOGYIF7.5
OAAI分享收藏Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse developmentCELL REPORTSOAAI
CELL REPORTSIF6.9
OAAI分享收藏分享收藏
查看更多内容