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Baseline immune signatures are associated with prospective COVID-19 infection and clinical outcomes in healthcare workers: evidence from a cohort study in Brazil
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DOI：10.1016/j.imlet.2026.107169.png)
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Abstract
En 中文
• Prospective COVID-19 diagnosis was linked to higher baseline levels of immune mediators; • Short-time onset and clinical outcome were related with higher levels of immune mediators; • Complex network structures underscore short-time onset, mild and short-lasting symptoms; • GM-CSF, CCL11, CXCL10 and TNF-α effectively categorized COVID-19(+) from COVID-19(-); • Decision-tree applies to time of disease onset, severity, symptoms duration and age.
Keywords:
COVID-19
SARS-COv-2
soluble immune mediators
chemokines
cytokines
growth factors
laboratory biomarkers
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