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Beating Poisson encapsulation statistics using close-packed ordering

delete2009-01-01
delete296
PRE
AI
A
Adam R. Abate
C
Chia‐Hung Chen
J
Jeremy J. Agresti
D
David A. Weitz *
DOI:10.1039/b909386adelete
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Abstract

Abstract

En 中文
Loading drops with discrete objects, such as particles and cells, is often necessary when performing chemical and biological assays in microfluidic devices. However, random loading techniques are inefficient, yielding a majority of empty and unusable drops. We use deformable particles that are close packed to insert a controllable number of particles into every drop. This provides a simple, flexible means of efficiently encapsulating a controllable number of particles per drop.
Keywords:
ON-A-CHIP
SINGLE-CELLS
MICROFLUIDIC DEVICE
DROPLET MICROFLUIDICS

Journal

L
Lab on a Chip
IF:
5.4
Papers:
9.0K
Citations:
3.3W

Organization

H
Harvard University
Scholars:
26.5W
Papers: 22.0W
Citations: 28.7W
U
University of Cambridge
Scholars:
7.7W
Papers: 7.1W
Citations: 13.7W