.png){kind=icon}
返回
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
摘要
En 中文
Binding studies were carried out on a vancomycin derivative to examine its
potential bactericidal activity. Of particular interest was the effect of
dimethylation of the amino group at the N-terminus of vancomycin on the
binding ability of the antibiotic to bacterial cell-wall peptide analogues,
namely Ac-D-Ala-D-Ala and Ac2-L-Lys-D-Ala-D-Ala.
Reductive methylation was carried out with sodium cyanoborohydride and
formaldehyde, and the binding constants of the vancomycin derivative with the
peptides were measured by ultraviolet difference spectroscopy.
期刊
暂无期刊信息
机构
暂无机构信息
引用论文
暂无论文信息