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Bioactive self-sensing optical systems

delete2009-12-22
delete60
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OA
AI
P
P. Domachuk
H
Hannah Perry
J
Jason J. Amsden
D
David L. Kaplan
F
Fiorenzo G. Omenetto *
DOI:10.1063/1.3275719delete
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摘要

摘要

En 中文
Free-standing silk films are useful materials to manufacture nanopatterned optical elements and to immobilize bio-dopants such as enzymes while maintaining their biological activity. These traits were combined by incorporating hemoglobin into free-standing silk diffraction gratings to fabricate chemically responsive optofluidic devices responsive to ambient gas conditions, constituting a simple oxygen sensor. This type of self-analyzing optical system is enabled by the unique ability to reproduce high-fidelity optical structures in silk while maintaining the activity of entrapped proteins such as hemoglobin. These bioactive optical devices offer a direct readout capability, adding utility into the bioresponsive material arena. (C) 2009 American Institute of Physics. [doi:10.1063/1.3275719]
Keyword:
MICROFLUIDIC DEVICES
SILK
OPTOFLUIDICS
INSECTS
SPIDERS
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期刊

Applied Physics Letters 封面图
Applied Physics Letters
IF:
3.6
论文数:
10.4W
被引数:
17.8W

机构

T
tufts university
学者数:
1.7W
论文数: 1.5W
被引数: 24
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