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Biocompatible 2D Materials via Liquid Phase Exfoliation
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DOI：10.1002/adma.202310999.png)
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Abstract
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2D materials (2DMs), such as graphene, transition metal dichalcogenides (TMDs), and black phosphorus (BP), have been proposed for different types of bioapplications, owing to their unique physicochemical, electrical, optical, and mechanical properties. Liquid phase exfoliation (LPE), as one of the most effective up-scalable and size-controllable methods, is becoming the standard process to produce high quantities of various 2DM types as it can benefit from the use of green and biocompatible conditions. The resulting exfoliated layered materials have garnered significant attention because of their biocompatibility and their potential use in biomedicine as new multimodal therapeutics, antimicrobials, and biosensors. This review focuses on the production of LPE-assisted 2DMs in aqueous solutions with or without the aid of surfactants, bioactive, or non-natural molecules, providing insights into the possibilities of applications of such materials in the biological and biomedical fields. 2D materials can be effectively produced by liquid phase exfoliation (LPE) using different conditions. LPE generates 2D materials in aqueous solutions, represented by graphene, black phosphorus, transition metal dichalcogenides and hexagonal boron nitride, and possess a huge potential in the biomedical domain, spanning cancer therapy, drug delivery as well as antimicrobial and biosensing. image
Keywords:
2D materials
bioactive molecules
bioapplications
biocompatibility
liquid phase exfoliation
Journal
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26.8
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3.4W
Citations:
46.0W
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Cited Papers