.png){kind=icon}
返回
BioMEMS device with integrated microdialysis probe and biosensor array
.png){kind=icon}
PRE
AI
DOI：10.1016/S0956-5663(02)00055-6.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The fabrication of a microdevice for continuous sampling and on-line monitoring of glucose is described. The device comprised a microdialysis sampling system integrated on the flow through channel of a microfabricated enzyme sensor. The sensor was produced by thin film technology and was assembled to a printed circuit board (PCB) that provided the means for both electrical and fluidic connections. A polyacrilonitrile fibre, with a cut-off of 50 kDa, was used in the fabrication of the sampling probe. The performance of the device was evaluated in-vitro. High sampling efficiency of the microdialysis probe was achieved by appropriate selection of the perfusion fluid flow rate. Response times varying from 1.5 to 3.0 min were determined for flow rates ranging between 1 and 0.2 mul/ min. The linear response range was up to 30 mM glucose and interference from other electroactive substances was almost negligible. The device showed excellent stability under continuous operation for at least 5 days and sensitivity variation less than 3% over a period of 15 days. (C) 2002 Elsevier Science B.V. All rights reserved.
Keyword:
glucose sensor
microdialysis sampling
continuous monitoring
microfabrication
BioMEMS
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
10.5
论文数:
1.8W
被引数:
7.7W
机构
暂无机构信息
引用论文
Thin-film glucose biosensor based on plasma-polymerized film: Simple design for mass production.png)
ANALYTICAL CHEMISTRY
ANALYTICAL CHEMISTRYIF6.7
PREAI
分享收藏In vitro optimisation of a microdialysis system with potential for on-line monitoring of lactate and glucose in biological samplesANALYST
ANALYSTIF3.3
PREAI
分享收藏
查看更多内容