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Biomimetic PLGA Nanofiber Scaffolds: Crystallization-Driven Mechanical Reinforcement and Degradation Kinetics Analysis

delete2026-06-06
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PRE
AI
J
Jinlong Zhu
S
Shuqiang Liu *
M
Mengjiao Ji
R
Rui Sun
Y
Yanan Yao
L
Lei Shao
M
Man Zhang
G
Gaihong Wu
P
Pengyu Yan
L
Lu Jia
Y
Yujing Zhang
DOI：10.1016/j.jmbbm.2026.107489delete
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Abstract

Abstract

En 中文
• Lotus-inspired scaffolds were fabricated via sequential electrospinning. • LA:GA 70:30 ratio induced a critical amorphous-to-semicrystalline transition. • Crystallization enhanced radial fatigue resistance via fiber bridging. • Semi-crystalline domains shifted the degradation mode from bulk erosion to progressive surface erosion. • Optimized surface wettability and biomimetic topology significantly promoted fibroblast proliferation.

Journal

Journal of the Mechanical Behavior of Biomedical Materials cover
Journal of the Mechanical Behavior of Biomedical Materials
IF:
3.5
Papers:
6.7K
Citations:
2.1W

Organization

T
taiyuan university of technology
Scholars:
5.4K
Papers: 1.7K
Citations: 0
S
shanxi medical university
Scholars:
1.7W
Papers: 7.9K
Citations: 114
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