返回
Biosensor-Assisted Engineering for Diverse Microbial Cellular Physiologies
DOI:10.1021/acs.jafc.4c04619.png)
摘要
En 中文
Recent advancements in biosensor technology have revolutionized the field of microbial engineering, enabling efficient and precise optimization of strains for the production of valuable chemicals. This review comprehensively explores the innovative integration of biosensors to enhance microbial cell factories, with a particular emphasis on the crucial role of high-throughput biosensor-assisted screening. Biosensor-assisted approaches have enabled the identification of novel transporters, the elucidation of underlying transport mechanisms, and the fine-tuning of metabolic pathways for enhanced production. Furthermore, this review illustrates the utilization of biosensors for manipulating cellular behaviors, including interactions with environmental factors, and the reduction of nongenetic cell-to-cell variations. This review highlights the indispensable role of biosensors in advancing the field of microbial engineering through the modulation and exploitation of diverse cellular physiological processes.
Keyword:
biosensor
cellular physiology
transport systems
metabolic network regulation
cellular behavior
期刊
IF:
6.2
论文数:
4.5W
被引数:
15.3W
机构
暂无机构信息
引用论文
A High-Throughput Method for Identifying Novel Genes That Influence Metabolic Pathways Reveals New Iron and Heme Regulation in Pseudomonas aeruginosa
MSYSTEMS
IF4.6
Riboswitch-guided chalcone synthase engineering and metabolic flux optimization for enhanced production of flavonoids核糖开关引导的查尔酮合酶工程和代谢通量优化以提高类黄酮的产量

