.png){kind=icon}
返回
Boosting extracellular vesicle secretion
.png){kind=icon}
OA
AI
DOI：10.1016/j.biotechadv.2022.107983.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
In recent years, extracellular vesicles (EVs), specifically exosomes, have emerged as a promising strategy for treating a wide spectrum of pathologies, such as cancer and COVID-19, as well as promoting tissue regeneration in various conditions, including cardiomyopathies and spinal cord injuries. Despite the great potential of EV-based therapies, poor yield and unscalable production of EVs remain big challenges to overcome to translate these types of treatment to clinical practices. Here, we review different strategies for enhancing EV yield by physical, biological or chemical means. Some of these novel approaches can lead to about 100-fold increase in EV production yield, thus bringing closer the clinical translation with regard to scalability and efficiency.
Keyword:
Extracellular vesicles
Exosomes
Large-scale
Drug delivery
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
12.5
论文数:
3.0K
被引数:
2.7W
机构
引用论文
Design strategies for materials showing thermally activated delayed fluorescence and beyond: Towards the fourth‐generation OLED mechanism显示热活化延迟荧光及以后的材料的设计策略: 迈向第四代OLED机制
PREAI
分享收藏分享收藏Hypoxia Inducible Factor-1α Potentiates Jagged 1-Mediated Angiogenesis by Mesenchymal Stem Cell-Derived Exosomes.png)
Stem CellsOAAI
Stem CellsIF3.6
OAAI分享收藏Increased PSA expression on prostate cancer exosomes in in vitro condition and in cancer patients在体外条件下和癌症患者中，前列腺癌外泌体上的PSA表达增加CANCER LETTERS
CANCER LETTERSIF10.1
PREAI
分享收藏
查看更多内容