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Brain cell activity detection using optical grating-based surface plasmonic resonance sensor

delete2025-06-28
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M
Masoumeh Taghilou
V
Vahid Ahmadi *
J
Javad Mirnajafi‐Zadeh
DOI:10.1016/j.sbsr.2025.100813delete
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摘要

摘要

En 中文
与其它方法相比,光学神经记录是无标记和无毒的。我们介绍了一种基于表面等离子体共振(SPR)和光学光栅的紧凑型、高可靠性膜活动检测传感器。我们利用光纤端口将光导向光学光栅,从而避免了笨重的光学设置。商用DVD作为光学光栅,既经济实惠又具有高质量。在该传感器中,我们将小鼠海马组织放置在溅射有金的(Au-sputtered)光栅上,并通过测量反射光谱,研究了SPR波长的偏移。引入高K+的aCSF溶液使我们能够轻松观察到细胞去极化对SPR波长的影响。所提出的传感器实现了628.06 nm/RIU的高灵敏度。
Keyword:
Membrane activity detection sensor
Optical grating
Surface plasmon resonance (SPR)
Neural activity
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期刊

Sensing and Bio-Sensing Research 封面图
Sensing and Bio-Sensing Research
IF:
4.9
论文数:
762
被引数:
2.6K

机构

T
Tarbiat Modares University
学者数:
1.4W
论文数: 1.3W
被引数: 1.4W
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