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Brimonidine Attenuates Choroidal Thinning and Hypoperfusion in Guinea Pigs with Form-Deprivation Myopia: Involvement of NOS and TGF-β1
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DOI：10.1016/j.ejphar.2026.178947.png)
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Abstract
En 中文
• SS-OCTA reveals spatial heterogeneity in choroidal thickness and perfusion in guinea pigs. • The C1–6 mm and superior regions exhibit heightened sensitivity to FD stimuli. • Brimonidine inhibits myopia by preserving choroidal thickness and perfusion. • Brimonidine prevents myopia via a choroidal mechanism involving NOS and TGF-β1.
Keywords:
Brimonidine
Choroidal thickness
Choroidal perfusion
Form-deprivation myopia
NOS
TGF-β1
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4.7
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2.3W
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4.0W
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