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Built to be imperfect

delete2024-07-05
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PRE
AI
J
Jie Xu
B
Bing Ren *
DOI:10.1038/s41556-024-01408-9delete
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摘要

摘要

En 中文
Transcription factors (TFs) and cis-regulatory elements (CREs) drive organism development. Suboptimal binding of TFs to CREs is shown to be key for the specificity of gene expression. New work now indicates that a similar principle governs the activities of TFs and their regulatory specificity.

期刊

Nature Cell Biology 封面图
Nature Cell Biology
IF:
19.1
论文数:
6.2K
被引数:
4.8W

机构

University of California System 封面图
University of California System
学者数:
37.5W
论文数: 33.7W
被引数: 6.6K