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Catatonia

delete2024-07-18
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PRE
AI
D
Dušan Hirjak *
J
Jonathan Rogers
R
Robert Christian Wolf
K
Katharina M. Kubera
S
Stefan Fritze
J
Jo Ellen Wilson
F
Fabio Sambataro
G
Gregory L. Fricchione
A
Andreas Meyer‐Lindenberg
G
Gábor S. Ungvári
G
Georg Northoff
DOI:10.1038/s41572-024-00534-wdelete
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摘要

摘要

En 中文
Catatonia is a neuropsychiatric disorder characterized by motor, affective and cognitive-behavioural signs, which lasts from hours to days. Intensive research over the past two decades has led to catatonia being recognized as an independent diagnosis in the International Classification of Diseases, 11th Revision (ICD-11) since 2022. Catatonia is found in 5-18% of inpatients on psychiatric units and 3.3% of inpatients on medical units. However, in an unknown number of patients, catatonia remains unrecognized and these patients are at risk of life-threatening complications. Hence, recognizing the symptoms of catatonia early is crucial to initiate appropriate treatment to achieve a favourable outcome. Benzodiazepines such as lorazepam and diazepam, electroconvulsive therapy, and N-methyl-d-aspartate antagonists such as amantadine and memantine, are the cornerstones of catatonia therapy. In addition, dopamine-modulating second-generation antipsychotics (for example, clozapine and aripiprazole) are effective in some patient populations. Early and appropriate treatment combined with new screening assessments has the potential to reduce the high morbidity and mortality associated with catatonia in psychiatric and non-psychiatric settings.
Keyword:
CLOZAPINE WITHDRAWAL CATATONIA
BRAINS RESTING STATE
MCCA PLUS JICA
SPATIOTEMPORAL PSYCHOPATHOLOGY
ELECTROCONVULSIVE-THERAPY
RATING-SCALE
FRONTOTEMPORAL DEMENTIA
SUBJECTIVE EXPERIENCE
AKINETIC CATATONIA
NEGATIVE AFFECT

期刊

N
Nature Reviews Disease Primers
IF:
60.6
论文数:
648
被引数:
3.8W

机构

R
Ruprecht Karls University Heidelberg
学者数:
5.6W
论文数: 4.3W
被引数: 66
U
University of Padua
学者数:
5.1W
论文数: 4.3W
被引数: 57
U
University College London
学者数:
7.9W
论文数: 6.2W
被引数: 15.7W
G
geriatric research education & clinical center
学者数:
2.9K
论文数: 2.2K
被引数: 4
U
US Department of Veterans Affairs
学者数:
3.8W
论文数: 3.3W
被引数: 47
V
veterans health administration (vha)
学者数:
2.6W
论文数: 2.1W
被引数: 40
U
university of london
学者数:
21.5W
论文数: 19.7W
被引数: 305
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