arrow
返回

CD3 ITAMs count!

delete2008-06-01
delete9
PRE
AI
B
Bernard Malissen *
DOI:10.1038/ni0608-583delete
delete原文链接
delete原文求助
delete分享
delete收藏
摘要

摘要

En 中文
The T cell receptor (TCR) is functionally coupled to a constellation of ten immunoreceptor tyrosine-based activation motifs (ITAMs). A new study suggests that this large number of ITAMs is mandatory for preventing autoimmunity.
Keyword:
T-CELLS
MICE
MUTATION
IMMUNITY
AI总结

AI总结

对已上传原文的论文进行重点信息的提取,主要内容包括:简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Nature Immunology 封面图
Nature Immunology
IF:
27.6
论文数:
6.4K
被引数:
5.6W

机构

暂无机构信息
引用论文

引用论文

Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions
errIMMUNITY
IF26.3
err2007-12-01
err130
errOAAI
errSiggs, Owen M.; Miosge, Lisa A.; Yates, Adele L.; Kucharska, Edyta M.; Sheahan, Daniel; Brdicka, Tomas; Weiss, Arthur; Liston, Adrian; Goodnow, Christopher C.
err分享
err收藏
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity
err2008-05-11
err154
PREAI
errHolst, Jeff; Wang, Haopeng; Eder, Kelly Durick; Workman, Creg J.; Boyd, Kelli L.; Baquet, Zachary; Singh, Harvir; Forbes, Karen; Chruscinski, Andrzej; Smeyne, Richard; van Oers, Nicolai S. C.; Utz, Paul J.; Vignali, Dario A. A.
err分享
err收藏
Prediction of survival of patients with primary biliary cirrhosis
err1992-01-01
err0
errOAAI
errFranklin M. Klion; Thomas L. Fabry; Melissa Palmer; Fenton Schaffner
err分享
err收藏
Crippling of CD3-ζ ITAMs does not impair T cell receptor signaling
errIMMUNITY
IF26.3
err1999-04-01
err105
errOAAI
errArdouin, L; Boyer, C; Gillet, A; Trucy, J; Bernard, AM; Nunes, J; Delon, J; Trautmann, A; He, HT; Malissen, B; Malissen, M
err分享
err收藏
Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells
err2008-02-01
err145
errOAAI
errWang, Ying; Kissenpfennig, Adrien; Mingueneau, Michael; Richelme, Sylvie; Perrin, Pierre; Chevrier, Stephane; Genton, Celine; Lucas, Bruno; DiSanto, James P.; Acha-Orbea, Hans; Malissen, Bernard; Malissen, Marie
err分享
err收藏
Simple conformation space search protocols for the evaluation of enantioselectivity of lipases
err1998-12-01
err0
PREAI
errC. Orrenius; C. van Heusden; J. van Ruiten; P. L. Overbeeke; H. Kierkels; J. A. Duine; J. A. Jongejan
err分享
err收藏
学者 查看更多内容