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Cefazolin administration prior to caesarean delivery and breastmilk microbiome: a nested cohort within a randomised clinical trial

delete2026-06-30
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OA
AI
V
Victoria Eley *
E
Elizabeth Martin
A
Akwasi Amoako
G
Gunter Hartel
K
Kate McCarthy
C
Christine Woods
Y
Yan Lu
J
Jian Tan
R
Ralph Nanan
J
Jeffrey Lipman
J
Jason Roberts
M
Mimi L.K. Tang
L
Leonie Callaway
S
Severine Navarro
DOI:10.1016/j.ijoa.2026.105222delete
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Abstract

Abstract

En 中文
• Antibiotics are administered prior to caesarean delivery to reduce infection. • Women were randomised to receive cefazolin or placebo prior to caesarean. • We compared the microbiome of breastmilk samples from the two groups. • There was no major dysbiosis from cefazolin exposure. • Demonstrable change in microbial maturation requires study in bigger numbers.
Keywords:
Composition
Cefazolin
Caesarean section
Infant, newborn
Intrapartum antibiotics
Microbiota
Milk, human

Journal

International Journal of Obstetric Anesthesia cover
International Journal of Obstetric Anesthesia
IF:
2.3
Papers:
341
Citations:
1.9K

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T
the university of sydney
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Medical School
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498
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the royal brisbane and women's hospital
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QIMR Berghofer Medical Research Institute
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5.2K
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murdoch children's research institute
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the university of queensland
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2.3K
Papers: 909
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