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Ceftriaxone-induced liver injury: Incidence, phenotypic characterization and predictive factors

delete2026-07-10
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OA
AI
M
Mohamed Hatem
M
Mohannad N. AbuHaweeleh
H
Humam Emad Rajha
M
Mhd Osama Rahhal
A
Ahmad Hamdan
L
Lina Naseralallah *
DOI:10.1002/bcp.70657delete
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Abstract

Abstract

En 中文
Ceftriaxone is a widely used third-generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug-induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed to evaluate the incidence, characterize clinical phenotypes, and identify risk factors for ceftriaxone-induced liver injury.
Keywords:
ceftriaxone
cholestatic injury
drug-induced liver injury
hepatotoxicity
incidence
predictors

Journal

British Journal of Clinical Pharmacology cover
British Journal of Clinical Pharmacology
IF:
3
Papers:
8.5K
Citations:
1.8W

Organization

H
Hamad Medical Corporation
Scholars:
1.1K
Papers: 491
Citations: 2.4K
Q
qatar university
Scholars:
1.6K
Papers: 779
Citations: 0
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