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Cell-free biomanufacturing

delete2018-12-01
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OA
AI
B
Bradley C. Bundy *
J
J. Porter Hunt
M
Michael C. Jewett
J
James R. Swartz
D
David W. Wood
D
Douglas D. Frey
G
Govind Rao
DOI:10.1016/j.coche.2018.10.003delete
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摘要

摘要

En 中文
Since its early development and use to decipher the genetic code, in vitro or 'cell-free' systems have been used as an important research tool to understand biochemical mechanisms and metabolic pathways. More recently, due to important engineering advances the technology is rapidly becoming a biomanufacturing platform for protein therapeutics, vaccines, enzyme biocatalysts, fuels, and commodity chemicals. Here we report recent applications and advances in the cell-free biomanufacturing field and the potential of this emerging approach.
Keyword:
FREE PROTEIN-SYNTHESIS
TRANSCRIPTION-TRANSLATION SYSTEM
FREE EXPRESSION
AMINO-ACIDS
FREE BIOSENSOR
FREE PLATFORM
IMPACT
QUANTIFICATION
GLUCOSE
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Current Opinion in Chemical Engineering 封面图
Current Opinion in Chemical Engineering
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1.2K
被引数:
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Stanford University
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Northwestern University
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