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Cell wall patterning regulates plant stem cell dynamics
DOI:10.1126/science.ady4102.png)
摘要
En 中文
植物细胞壁通过对其化学和机械特性的时空调控来调节发育。果胶甲酯化被认可为控制壁刚度的流变学开关。本研究揭示了在分生组织中存在双模态甲酯化模式:成熟壁表现出高甲酯化,而脱甲酯化果胶则沉积在新形成的交叉壁中。这种空间异质性是通过果胶甲酯酶5(PME5)mRNA的核隔离建立的。MYB3R4驱动的转录,结合RZ-1B/1C介导的滞留,在细胞核中形成了与有丝分裂相关的PME5 mRNA储存库。核膜解体将PME5信使RNA(mRNA)的释放与细胞板形成同步,从而在分裂面实现精确的脱甲酯化。对这种空间控制的干扰会破坏干细胞维持或打破分裂模式。本研究揭示了一种mRNA区室化机制,将干细胞动力学与果胶修饰联系起来。
Keyword:
MESSENGER-RNA
METHYL-ESTERIFICATION
PECTIN STRUCTURE
PLATE FORMATION
MORPHOGENESIS
GENE
DIVISION
MERISTEM
GROWTH
MODEL
期刊
IF:
45.8
论文数:
1.4W
被引数:
78.6W
机构
引用论文
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