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Characterizing Cutaneous α-Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
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DOI：10.1002/acn3.70465.png)
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Abstract
En 中文
Cutaneous phosphorylated α-synuclein (p-syn) and α-synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype-specific diagnosis and disease severity assessment.
Keywords:
immunostaining
Parkinson's disease
phosphorylated α-synuclein
α-synuclein seed amplification assay
α-synuclein seeding activity
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