Characterizing DNA mixtures with Demixtify

August E. Woerner

doi:10.1016/j.fsigen.2026.103451

2026-02-18

PRE

August E. Woerner *

Benjamin Crysup

Michael D. Coble

DOI：10.1016/j.fsigen.2026.103451

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摘要

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• 考虑低通量和高通量全基因组测序。 • 可检测低至0.01×基因组含量的混合物。 • 提供混合比例的点估计值和置信区间。 • 可准确表征高覆盖度（≥1×）基因组中的混合物。 • 引入一套低FST标记的自定义面板，以减少种群结构的影响。

Keyword:

DNA mixtures

whole genome sequencing

mixture proportion

confidence interval

low FST markers

期刊

forensic science international: genetics

IF:

论文数:

107

被引数:

机构

university of north texas health science center

学者数:

论文数: 25

被引数: 0

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