1
Return

Chemokine dynamics after mRNA vaccination

delete2026-05-05
delete0
delete
OA
AI
L
L. Marques Palma
S
Sebastian Schlaweck
C
Chrystel Flores
H
H. Aslan
C
C. Kurts
P
P. Brossart
J
Janine Becker-Gotot
A
Annkristin Heine *
DOI:10.1016/j.imlet.2026.107183delete
deleteOriginal
deleteShare
deleteSave
View PDF
Abstract

Abstract

En 中文
• mRNA-1273 vaccination causes chemokine and cytokine alteration peaking on days 1-4 post vaccination • T cell and monocyte subpopulations display most numerical changes following mRNA-1273 vaccination • Activated CD4+ T cells, activated CD8+ T cells and Tregs show increased expression of CXCR5 and CCR1/6/7, respectively, peaking on day 1-4 post vaccination • RBD+ B cells increase expression of chemokine receptors CCR4/5, CXCR4/5 peaking on day 3-7 post vaccination
Keywords:
COVID-19
SARS-CoV-2
chemokines
T cells
mRNA vaccination
B cells
monocytes
NK cells
APC
antigen-presenting cell
BM
bone marrow
CCL
chemokine C-C-motif ligand
CCR
chemokine C-C-motif receptor
COVID-19
coronavirus disease 2019
CTL
cytotoxic T lymphocyte
CXCL
chemokine C-X-C-motif ligand
CXCR
chemokine C-X-C-motif receptor
DC
dendritic cell
GM-CSF
granulocyte macrophage-colony stimulating factor
ICAM-1
intercellular adhesion molecule 1
IFN(α)
interferon alpha
IL-(6)
interleukin-(6)
MHC-I
major histocompatibility complex class I
MHC-II
major histocompatibility complex class II
NAb
neutralizing Antibodies
NK
natural killer (cell)
SARS-CoV-2
severe acute respiratory syndrome virus 2
TFH
T follicular helper (cell)
Th1
T helper 1 (cell)
Th17
T helper 17 (cell)
TLR
Toll-like receptor
TNF(α)
Tumor necrosis factor alpha
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Immunology Letters cover
Immunology Letters
IF:
2.8
Papers:
4.5K
Citations:
6.1K

Organization

I
institution
Scholars:
182
Papers: 84
Citations: 0
Cited Papers

Cited Papers

Citing Papers

Citing Papers