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Childhood adversity is associated with longitudinal white matter changes after adulthood trauma

delete2025-09-17
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OA
AI
T
Tianyi Li
M
Megan E. Huibregtse
T
Timothy D. Ely
S
Sanne J.H. van Rooij
L
Lauren A. M. Lebois
E
E. Kate Webb
T
Tanja Jovanović
S
Stacey L. House
S
Steven E. Bruce
F
Francesca L. Beaudoin
X
Xinming An
T
Thomas C. Neylan
G
Gari D. Clifford
S
Sarah D. Linnstaedt
K
Kenneth A. Bollen
S
Scott L. Rauch
J
John P. Haran
A
Alan B. Storrow
C
Christopher Lewandowski
P
Paul I. Musey
P
Phyllis L. Hendry
S
Sophia Sheikh
C
Christopher W. Jones
B
Brittany E. Punches
L
Lauren A. Hudak
J
José L. Pascual
M
Mark J. Seamon
E
Elizabeth M. Datner
C
Claire Pearson
D
David A. Peak
R
Roland C. Merchant
R
Robert M. Domeier
N
Niels K. Rathlev
B
Brian J. O’Neil
P
Paulina Sergot
L
León D. Sánchez
J
John F. Sheridan
R
Ronald C. Kessler
K
Karestan C. Koenen
K
Kerry J. Ressler
S
Samuel A. McLean
J
Jennifer S. Stevens
N
Nathaniel G. Harnett *
DOI:10.1016/j.bpsc.2025.09.007delete
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Abstract

Abstract

En 中文
Childhood adversity is associated with susceptibility to posttraumatic stress disorder (PTSD) in adulthood. PTSD and childhood adversity are linked to white matter microstructure, yet the role of white matter as a potential neural mechanism connecting childhood adversity to PTSD remains unclear. The present study investigated the potential moderating role of previous childhood adversity on longitudinal changes in white matter microstructure and posttraumatic stress symptoms following a recent traumatic event in adulthood.

Journal

Biological Psychiatry-Cognitive Neuroscience and Neuroimaging cover
Biological Psychiatry-Cognitive Neuroscience and Neuroimaging
IF:
4.8
Papers:
1.3K
Citations:
4.4K

Organization

I
Institute for Trauma Recovery
Scholars:
3
Papers: 2
Citations: 0
O
Ohio State University College of Medicine
Scholars:
16
Papers: 12
Citations: 0
M
Massachusetts General Hospital
Scholars:
3.4W
Papers: 2.6W
Citations: 8.6W
B
Brown University
Scholars:
2.4W
Papers: 2.2W
Citations: 3.2W
U
university of california san francisco
Scholars:
5.2W
Papers: 4.0W
Citations: 66
E
emory university school of medicine
Scholars:
1.4K
Papers: 624
Citations: 0
H
Harvard University
Scholars:
26.2W
Papers: 21.9W
Citations: 28.7W
D
Department of Sociology
Scholars:
276
Papers: 205
Citations: 0
Detroit Receiving Hospital cover
Detroit Receiving Hospital
Scholars:
2
Papers: 2
Citations: 142
M
McLean Hospital
Scholars:
1.6K
Papers: 1.1K
Citations: 4.0K
U
university of pennsylvania
Scholars:
9.2W
Papers: 7.8W
Citations: 152
J
john hospital
Scholars:
5
Papers: 3
Citations: 0
U
University of Massachusetts Chan Medical School
Scholars:
518
Papers: 168
Citations: 2.0W
V
Vanderbilt University Medical Center
Scholars:
2.0K
Papers: 775
Citations: 2.3W
I
Indiana University School of Medicine
Scholars:
1.1K
Papers: 508
Citations: 1.9W
H
Henry Ford Health System
Scholars:
9.1K
Papers: 7.4K
Citations: 3.4K
W
wayne state university
Scholars:
2.0W
Papers: 1.6W
Citations: 17
T
trinity health-ann arbor
Scholars:
1
Papers: 1
Citations: 0
J
Jefferson Health
Scholars:
13
Papers: 12
Citations: 0
D
Department of Emergency Medicine
Scholars:
799
Papers: 355
Citations: 1
H
Harvard Medical School
Scholars:
6.5W
Papers: 4.8W
Citations: 91
W
Washington University School of Medicine
Scholars:
2.7K
Papers: 830
Citations: 0
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